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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRAP1
All Species:
39.7
Human Site:
Y2105
Identified Species:
87.33
UniProt:
P42345
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42345
NP_004949.1
2549
288892
Y2105
T
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535407
2550
288910
Y2106
T
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLN9
2549
288718
Y2105
T
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Rat
Rattus norvegicus
P42346
2549
288776
Y2105
T
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510680
2493
282092
Y2049
T
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Chicken
Gallus gallus
XP_417614
2463
280042
Y2023
T
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070679
2515
286136
Y2071
T
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VK45
2470
281015
Y2026
D
R
A
W
D
I
Y
Y
H
V
F
Q
K
I
S
Honey Bee
Apis mellifera
XP_625130
2442
278856
Y2004
N
Q
A
W
D
L
Y
Y
H
V
F
R
R
I
S
Nematode Worm
Caenorhab. elegans
Q95Q95
2697
306510
C2281
N
Q
A
W
E
I
Y
C
S
V
F
K
K
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32600
2474
281549
Y2045
N
Q
A
W
D
I
Y
Y
N
V
F
R
K
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.4
N.A.
98.9
98.9
N.A.
88.8
93.7
N.A.
89.8
N.A.
54
62
34.7
N.A.
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99.2
99.2
N.A.
91.2
95.4
N.A.
94.5
N.A.
69.8
75.7
53.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
66.6
93.3
40
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
93.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
91
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
28
0
0
0
0
0
0
0
91
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
28
0
0
% K
% Leu:
0
0
0
0
0
73
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
28
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
91
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
82
73
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
82
% S
% Thr:
64
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% V
% Trp:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
100
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _